Bionic Eyeball Implant Design Features

Here, we present a description of a stop scheme, specific features of design and results of testing for a prototype of a bionic eyeball, types of them and its applications. The bionic eyes is intended to provide eye-sight, partially to the aesthetically impaired by use of the modern day consumer electronics devices like CCD surveillance cameras. The comprises your personal computer chip that rests in the back of the individual's eyesight, linked up to tiny video camera included in eyeglasses that they wear. Images captured by the camera are beamed to the chip, which translates them into impulses that the brain can interpret. Even though images produced by the artificial eyesight were far from perfect, they could be clear enough to allow someone who is normally blind to identify faces. The newspaper discusses the variations working methodologies found in each of them. During the checks and the scientific trails, this device made six blind visitors to regain their perspective partially. The actual benefit of using bionic eyes is to be able to take away the blindness completely by making the advances in the present research and bettering manufacturing technologies. This break through will probably benefit about one crore world inhabitants who have problems with the most common factors behind blindness, Retinitis Pigmentosa, Macular Degeneration. The implant bypasses the diseased cells in the retina and stimulates the rest of the viable cells. This is a revolutionary little bit of technology and really has the potential to change people's lives. But we need to take note it is still some way in the foreseeable future.

A Bionic Eyes is a tool, which operates as an artificial eye. It is a broad term for the whole electronics system comprising the image sensors, processors, radio transmitters & receivers, and the retinal chip. Predicated on the institute developed the unit are developed but with modest to major variances, of these the devices with practical capability and those which are clinically examined and results demonstrated are discussed here. Here the designer's objective is to go for a system that is technically perfect without loop holes and that is harmless to our body which receives the machine that is certainly commercially practical both in terms of ease of manufacture, cost and the process of implanting.

Blindness means loss of eye-sight. Rods and Cones, an incredible number of them are in the back of every healthy eye. They are biological solar panels in the retina that convert light to electric impulses -- impulses that travel over the optic nerve to the mind where images are shaped. Without them, eyes lose the capability to see, and are declared blind. Degenerative retinal diseases result in fatality of photoreceptors--rod-shaped cells at the retina's periphery accountable for night vision and cone-shaped skin cells at its middle responsible for color eye-sight. Worldwide, 1. 5 million people have problems with retinitis pigmentosa (RP), the primary reason behind inherited blindness. In the Western world, agerelated macular degeneration (AMD) is the major cause of vision reduction in people over age 65, and the problem is becoming more critical as the populace ages. Each year, 700, 000 people are diagnosed with AMD, with 10 percent becoming lawfully blind, identified by 20/400 perspective. Many AMD patients preserve some extent of peripheral vision.

Currently, there is no effective treatment for most patients with AMD and RP, the research workers say. However, if one could bypass the photoreceptors and straight stimulate the inner retina with visible signals, one could probably restore some extent of perception.

Need for the BIONIC EYE:

It has been shown that electric activation of retinal neurons can produce perception of light in patients experiencing retinal degeneration. By using property the attention and make uses of the functional cells to retain the vision with the help of gadgets that assist this skin cells in performing the task of vision, we can make these lakhs of individuals reunite their vision at least artially. A design of an optoelectronic retinal prosthesis system that can activate the retina with resolution related to a visible acuity of 20/80-razor-sharp enough to orient yourself toward objects, recognize faces, read large fonts, watch Television and, perhaps most important, lead an independent life. The experts pray their device may someday bring unnatural vision to prospects blind scheduled to retinal degeneration.

BIONIC EYE DEFINED:

Bionic Eyeball, Bio Electronic eyesight, is a device that can provide look - the recognition of light. It replaces the efficiency of a component or entire of eye. it is utilized to replace efficiency as well as add features. It really is a complex mixture of multiple devices which work together for restoration of the eye-sight of the topic.

The Diseases that cause blindness:

  • Retinitis Pigmentosa
  • Macular Degeneration

Of these, retinitis pigmentosa is a disease, which is a hereditary genetic disease in which peripheral rods degenerate slowly but surely progresses towards center of eye and leads to tunnel vision.

As for macular degeneration, it is also genetically related, it degenerates cones in macula region, leading to damage to central vision but spares peripheral retina.

MIT- HARVARD DEVICE:

This device comes after an Epi-Retinal Strategy. In such a Microelectrode array replaces destroyed photoreceptors, which work instead of rods and cones to send the signals to optic nerve. The energy source - Laser(820nm wavelength). For image acquisition it runs on the CCD Camera. Patient spectacle retains the camera and vitality source.

It involves two systems, system-1 which senses and transmits image and vitality and other system which stimulates the cells, there by causing brain imagine the image.

System 1:

  • CCD camera insight - External light intensity
  • CCD output amplitude-modulates laser source
  • This hits photodiode selection of implant
  • This subsequently powers stimulator chip (SC)

System 2:

  • SC drives current to electrodes facing retina
  • This excites the ganglionic cells > axons > optic nerve > visual cortex in occipital lobe of brain
  • Brain helps in perceiving an image

Advantages:

  • Very Early in the visual pathway
  • No Batteries implanted within body
  • No complicated operative procedure
  • Power Necessity - ј of milliwatt

Disadvantages

  • Axons b/w electrodes and ganglionic cells
  • Other axons get thrilled - unwanted understanding of large blur
  • Extra circuitry required for downstream electric powered input

Artificial Retina Prosthesis using ASR (Artificial Silicon Retina)

ASR is a good condition biocompatible chip which contains a range of photo receptors, and is implanted to displace the features of the defective photoreceptors. Current produced by the device in response to light

stimulation will alter the membrane probable of the overlying neurons and in that way activate Visual ensationsthoerv "iPsuhaolsspyhsetenmes. " can be evoked by electrical stimulation of the different degrees of the aesthetic pathway. Phosphenes are evoked by the activation of the eyeball or the visible cortex. Artificial vision created by the manipulated electric arousal of the retina has color.

Epiretinal Approach consists of a semiconductor based mostly device added to the top of retina to attempt to simulate the remaining overlying cells

Sfutbhreerteintianla Approach entails implanting the ASR chip behind the retina to simulate the remaining viable skin cells.

IMPLANT DESIGN:

Primitive devices

Single photosensitive pixel(3mm in diameter)

Neo devices

The current micro photodiode array (MPA) is comprised of a regular array of individual hotodiode subunits, each roughly 20-20-јm square and separated by 10-јm route ceases (37). The producing micro photodiode denseness is roughly 1, 100/m2.

IMPLANT features

The size of implant is 50um. And it needs no external power. The response 500nm to 1100nm wavelength response.

Working:

For the technique to work, the patient must still involve some functioning ganglion skin cells - nerve cells that transmit visual information from the retinal skin cells to the optic nerve - and a fully-functioning optic nerve. A little digital pad is located onto the retina of one eye, so the electrodes are in immediate contact with the ganglion cells. Each of the devices' 100 electrodes can promote 20 to 30 cells.

Real-time vision:

The end user wears a pair of glasses which contain a miniature camera and that wirelessly transmits video to a cellphone-sized computer in the wearer's pocket. This computer steps the image information and wirelessly transmits it to a little electronic receiver implanted in the wearer's head.

When received in the implanted chip, the digital information is changed into electric impulses sent into the ganglion cells. After that, the brain takes over as the info vacations down the optic nerve to the visible cortex at the back of the brain. The complete process occurs extremely swiftly, so that patients see in real-time. That is important any apparent lag could activate the "vestibular-ocular reflex", making people feel dizzy and tired.

Currently recipients of the device experience a relatively thin view, but more electrodes should give a greater field of eye-sight. By revitalizing more ganglion cells, he hopes that visible acuity will increase significantly. His team's next goal is to design a device with 1000 electrodes.

MANUFACTURING PROCESS:

Implants are made up of a doped and ion-implanted silicon substrate disk to make a PiN (positive-intrinsic-negative) junction. Fabrication commences with a 7. 6-cm diameter semiconductor class N-type silicon wafer.

For the MPA device, a photomask is employed to ion-implant shallow P+ doped wells in to the front surface of the wafer, segregated by channel halts in a style of specific micro photodiodes. An intrinsic layer automatically sorts at the boundary between your P+-doped wells and the N-type substrate of the wafer. The trunk of the wafer is then ion-implanted to make a N+ surface. Thereafter, an insulating part of silicon nitrate is deposited on leading of the wafer, covering the whole surface except for the well openings. A slim adhesion level, of chromium or titanium, is then transferred within the P+ and N+ layers. A clear electrode covering of silver, iridium/iridium oxide, or

platinum, is deposited on the front well side, and on the background part. In its simplest form, the photodiode and electrode tiers are the same size. However, increasing the photodiode collector to electrode area ratio can increase the current density available at every individual micro photodiode subunit. Post Implant function and Inference.

Measurement procedure

  • IR excitement at 940nm on the ASR chip
  • Recorded at the corneal surface using contact lens electrode
  • Comparison of replies of platinum, platinum and iridium electrodes
  • Iridium structured device has a longer persistence
  • Stability of these electrodes

BIO-COMPATIBILTY RESULTS:

There is not any intensifying change in retinal appearance which may be associated with retinal toxicity. But there exists lack of photoreceptive part over the spot of implant, which is expected scheduled to deprival of oxygen and nutrients to prospects cells root the chip.

Multiple Product Artificial Retina Chipset (MARC):

The other revolutionary bio electronic eyeball is the MARC, this runs on the ccd camera input and a laser beam or rf to transfer the image into the chip present in the retina. by using this an answer of 100 pixels is attained by utilizing a 10x10 array. It includes a platinum or plastic silicon electrode array located inside the eye to activate the cells.

The sensing of the light is done using the sensor shown in the aforementioned figure.

THE MARC SYSTEM Stop:

Outside Eyesight:

The video source to the marc system stop is given through the CCD camera. This image is further prepared utilizing a PDA size image processor & to transfer it, we do pulse width modulation in first level and then ASK modulation is done.

This indication is further amplified by using a class E electric power amplifier and sent using RF telemetry coils.

Inside Vision:

The indication received from the RF telemetry coils is vitality retrieved and then these indication is ASK demodulated and the info and clock is recovered from this indicators and these indication are delivered to the construction and control stop of the chip which from its input decode what information must be sent to each of the electrodes and directs them this data. And the electrodes in turn stimulate the cells in the eye in order to send this activation to the mind through optic nerve and

help brain in visualizing the image even though this process is certainly going on the position of each electrode is sent to the marc diagnostics chip beyond your eye

Block Diagram Of Image Acquisition System:

The image acquisition system includes a CMOS camera which acquires images and directs it to the Analog to Digital Converter. It changes this analog input to digital data. This data is first sent into a video recording buffer where it is processed, the images are color mapped and this processed images are directed through RS232 software. this serial data is then sent to the electrodes or evaluation monitor by having a RF circuit or laser.

Marc Hermetic Closing And Positioning:

The RF coils either intra ocular or extra ocular coil set up as shown in number. This rf probes receives the sent RF energy and present it to the MARC chip. The AC wires from this coil is sent to the MARC chip. This chip is

hermetically covered in silicon gel and the other sides of the chips have electrodes, which promote the skin cells in vision.

Advantages of the Marc system:

  • Compact Size - 6x6 mm
  • Diagnostic Capability
  • Reduction of stress upon retina

Conclusion:

Researchers across the world have seemed for ways to improve people's lives with unnatural, bionic devices. Its been 40 years since Arne Larsson received the first completely implanted cardiac pacemaker. Experts throughout the world have appeared for ways to improve people's lives with artificial, bionic devices. Bionic devices are being developed to do more than replace defective parts. Experts are also with them to fight health problems.

Providing capacity to run bionic implants and making relationships to the brain's control system present both great obstacles for biomedical executive. But whichever be the pro and cons of this system. If this system is fully developed it will change the lives of

millions of individuals across the world. We may well not restore the eyesight completely, but we can help them to least have the ability to find their way, recognize faces, read books, above all lead an unbiased life.

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