Inotropy can have positive or negative effect on the center, especially the ventricles. You will find few factors that can influence inotropy; this can either be neuronal, hormonal. The neuronal effect is predominately from the autonomic nerves, either the parasympathetic or the sympathetic nerves and these have both negative and positive influence on inotropy. However, other affects come from some drugs which have positive or negative effect on inotropy. This can consequently..