In last few years pharmaceutical industries facing obstacles because of financial downturn, increased healthcare cost, surge development cost, pharmaceutical sales on the market, increased competition for general medicine products, regulatory pressure cause weak US pharmaceutical progress. Few blockbuster drugs come to the marketplace Because of lowered New Substance Entities (NCE) research, development & marketing. Pharmaceutical manufacturing sector performs serious role in US current economic climate. Manufacturing and Good Syndication Practice (GDP) for pharmaceutical drug products diminishes as compare to previous few years. But at exactly the same time, Chinese share increases up to 17%. It is important part of US economy, but processing is forget about prevailing part of US current economic climate. Finally some business adapted few answers to conquer problems. Analyst targets commercial view of the companies and gives some advice that use in current market and successful future.
Objective
Small scale & large level manufacturing companies have to take into account their production in growing global market. The primary object of matter is to judge and view future of the manufacturing practice in global market by creating model. Due to expansion of market, companies have to lessen making cost to stand in competition, raise profits and market talk about on expanding goal audience. They create new medication products in the market and keep maintaining required quality of the drugs with low cost to hold their regular customer and get clients.
Figure 1 Shape Work Diagram
Global Environment
Companies will preplan before any outsider influence the manufacturing procedure for the medication product. Company can aware of market economy, globalization, latest technologies develop in production field, demographics etc.
Strategic Responses
Strategic response in pharmaceutical processing can be used in development flexibilities, create design of new medication product, new making process with newly discover medicine products, reference to internet which gives good communication between employees and data.
SME Recommendations
In last step, more concentrate on prescription information then description information. Main target of prescriptive strategy is on customer satisfaction, market scenario, newly develop technologies in the pharmaceutical field and networking.
Business Strategy
First of all companies are aware of market, competition, relative drug manufacturing, materials and work costs, governments legal policies as per countries guidelines. Create an idea and criteria to achieve successful marketing, saving cash and revenue, highly trained staff & new solutions with freshly established goals running a business sector. It offers financial exploration, business fact, material sourcing, stock management, developing, in process management, circulation, campaign and marketing management. Changes in the global market is extremely swift so by using metrics and management suggestions to increases business strategies, add and improve necessary data running a business. Management can provide change to every staff for their individual suggestion to boost business strategy. [1]
Growing Environment
Manufacturing of 1 medicine product is trial to do. Because it to difficult to understand demand of the drug product in approaching few years. Company may spend huge amount of money for new drug manufacturing, its authorization, marketing and advertising. If drug cannot cross in scientific trial due to its undesired undesireable effects more than its gain, so company has to spend money and time to resolve this problem. Company spent 3 to 4 4 years and billions of dollars for building center for particular kind of medication product and there is no security that the new product is №cost effective and suitable enough to fit in companys requirements & profitable enough for the business. [2] Generic medication companies do not face these types of problems as well as the margin of profit is less as compare to the BRAND Medication Company.
Just in Time (JIT) in manufacturing
Just in time is a move method of creation. Just in time is applied in medication manufacturing process which can be used to diminish in process methods and time.
JIT is suitable production arrangement when: [3]
Specific variety of the products prepared by manufacturing process
Drug products with high value
Less time setup for medicine on machine
Highly trained staff and versatility in work
Standard product with stable production
Quality of the merchandise can be ensured
Just in time is used to boost drug product quality and performance. Particular level of the raw material which is given by the company is cut down at the particular level then company can order new raw materials in the business so it really helps to save space in warehouse and reduce to check physical and chemical test of the raw materials. First of all it was found in ford engine company by Henry Ford. [4] It essentially targets management as well as how to implement supply string in to the specific developing process. JIT provides clear increase in liquid advantage of the business by creating tax free and cashflow. Company release new drug product into the market at that time low outcome time is beneficial for unexpected upsurge in drug need. Long end result time is generally making detail list of all the items in stock of the drug product before increasing the demand of product. If we can use JIT in pharmaceutical production which is bad decision because company has to spent additional money to create durable method. So we can say that if generic medication product companies use JIT procedure is beneficial to them as compared to Brand Name Medication Company. Margin of the saving money by the general medicine product companies are less then BRAND Medicine Company. [5]
Weakness of JIT
JIT normally used in highly automatic medication production but not in custom made item. Everyone relies on others because they are mutually dependent to one another. Weakness of JIT affects on supply chain and it become more costly. It causes drug market fluctuation, inappropriate stock, insufficient communication atlanta divorce attorneys stage and also may leads to decrease drug development. [6] Sometime small level of materials has been used to conquer defective medicine product end result. If supplier is not going to supply raw materials with time to the company, it cause hold off in production and distribution. Particular space is used for completed product so astonishing order creates problems in completed product team.
Global Pharmaceutical Market
Figure 2 Global Pharmaceutical Industry
Nowadays expansion of pharmaceutical marketplaces on the globe is 4 to 6% & expected value is $825 billion. As per professionals review, progress of pharmaceutical market is increase up to 4 to 7 % by 2013. And expected value of the market increase up to $975+ billion by 2013. In recent scenario, pharmaceutical marketplaces are growing fast around Asia-Pacific. For the reason that of suprisingly low cost and beneficial environment with contract manufacturing and general drug production. Increased in Reach and Development market in this area was helped to gain money up to US $187 billion in '09 2009. Now limited companies are involved in R& D program. Sometime Research & Development takes more time needlessly to say so budget boosts but company cannot increase product cost scheduled to government procedures. Because of this companies aren't hanging out for new medication Research & Development. Latest growing pharmaceutical companies are in India, China, Indonesia, South Korea, and Malaysia anticipated to less cost of the medication product, less labor cost, good medical health insurance strategies as compare to the US market and it is beneficial to the company for its growth. China possibly becomes biggest pharmaceutical market on the planet. India is another largest maker of prescription product in the world. Expected expansion of the pharmaceutical industries in global market in approaching years is within China and Russia because they have strong support of government. [7]
Demographic in pharmaceutical market
With the help of research we can know the demographic review, macroeconomic indications, disease evaluation etc. It can be used to learn the strategies in the market and successful opportunities in the global pharmaceutical market. Some topics which helps in demographic review such as:
Analyst View
Basically analyst bank checks all details of clinical study, assess them if any problem in machine, real human error, quality control system, in process methods etc, will come in the analysis, if so they can conquer the problem and improve with the help of specific method. It helps to save money by increasing product quality. [8]
Control in functioning cost
How to boost quality with less cost of the medicine product is very challenging in pharmaceutical market. Understanding cost way is used to increase margin of the medicine manufacturing. Pharmaceutical industries have to take dynamic steps to be able to regulate cost. Cost of Research and Development raises upon breakthrough of new blockbuster in the market.
Attracting and having skilled workers
In pharmaceutical business, experience and knowledge in the employees is vital. Folks who are working in the business are skilled with good knowledge about market, excellent communication skill, Professional action, unity, in a position to manage work fill etc. have an effect on the development of company. Labor cost of america is high as compare to China & India. [9]
Pharmaceutical Companies facing Challenges
Pharmaceutical companies are facing difficulties to build up high quality of medication product with less cost due to increase human population on the planet. To build quality of the drug products give less yield and high market cost, consequently consumer may well not use medicine product. To resolve this problem company has to create new development formulas. They spend billions of dollars because of its research; developments, endorsement, advertisement and marketing with less medication cost without reducing gross send on R & D. Companies have to handle some geo-political situation. For example; AIDS is major problem on earth. Governments are requiring strict attention on Supports and give pressure to pharmaceutical companies to find & develop new medication product which is utilized to cure AIDS. Brand Name Medicine Company has to face some issues because following the patent expiry they can be allowed new product in to the market, so other companies create same medication which are equivalent to brand name medication in all respects is called as General Drugs. Generic maker don't need to get money and time for R& D, as grounds common drugs are less costly. Market talk about of Brand Name Medicine is declines anticipated to generic medication. Health insurance promotes the generic medication use one of the consumers for saving bills therefore less research on new drugs. Following are some solution which really helps to overcome some issues facing by pharmaceutical companies.
Figure 3 Some Solution stack & Positioning with Pharmaceutical Tendencies & Aspirations
Pharmaceutical solution provides new and unique way for solubility profile predicated on medicine properties and changing some process for medicine development. These alternatives provide management features through various procedures leading to improve in work for high level of efficiency. It is very flexible and is applicable enough in Dynamic Pharmaceutical Ingredients, DP and Biotechnological medication manufacturing. With the help of true SOPs, we can check manual problems done by employees evaluate it and create a fresh process how to resolve this problem. ISA-95 and ISA-88 is utilized to define challenges face by clients in general management, process examination, in its data, in plan etc.
Conclusion
As per my opinion JIT is very helpful system for developing company with wide consignment, suitable material with quality, employees, and different types of accessories can always accessible when required. JIT diminishes product waste and good quality of products which is prepared by manufacturer, provider and consumer. In a nutshell, JIT is a one of the Ladder with continuous stages of devotion to do job in proper way in growing global market. Nowadays pharmaceutical sectors face many issues of making it through in this global market. Universal producer are facing competition for common products, induce for restrict drug price credited to government guidelines and increase R&D cost scheduled to governmental requirements. Active pharmaceutical Ingredients production started in china and India before couple of years.
